The Human Brain
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- Category: Human Anatomy
- Published on Saturday, 08 November 2008 14:30
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The brain is the center of the nervous system in all vertebrate and most invertebrate animals. In vertebrates the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell.
Brains can be extremely complex. The cerebral cortex of the human brain contains roughly 15–33 billion neurons, perhaps more, depending on gender and age, linked with up to 10,000 synaptic connections each. Each cubic millimeter of cerebral cortex contains roughly one billion synapses. These neurons communicate with one another by means of long protoplasmic fibers called axons, which carry trains of signal pulses called action potentials to distant parts of the brain or body and target them to specific recipient cells.
The brain controls the other organ systems of the body, either by activating muscles or by causing secretion of chemicals such as hormones and neurotransmitters. This centralized control allows rapid and coordinated responses to changes in the environment. Some basic types of responsiveness are possible without a brain: even single-celled organisms may be capable of extracting information from the environment and acting in response to it.
In vertebrates, the spinal cord by itself contains neural circuitry capable of generating reflex responses as well as simple motor patterns such as swimming or walking. However, sophisticated control of behavior on the basis of complex sensory input requires the information-integrating capabilities of a centralized brain. Despite rapid scientific progress, much about how brains work remains a mystery. The operations of individual neurons and synapses are now understood in considerable detail, but the way they cooperate in ensembles of thousands or millions has been very difficult to decipher.

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