Gene Therapy Review
Welcome to our gene therapy portal
The Gene Therapy Review is the web resource for patients and professionals interested in cell and gene therapy. Founded in 2008, the aim of the site is to be an information resource for basic and clinical research in the fields of gene therapy, cell therapy, and genetic vaccines, and to serve as a network in the exchange of information and news related to this arena. We welcome contributions from researchers and clinicians alike with a view in increase awareness in this vastly growing sector.
Gene Therapy in the News
Early indicators of the malaria parasite in Africa developing resistance to the most effective drug available have been confirmed, according to new research. Investigators found Plasmodium falciparum malaria parasites with a mutation to the gene Ap2mu were less sensitive to the antimalarial drug artemisinin.
Children with 'bubble boy disease' who undergo gene therapy have fewer infections and hospitalizations than those receiving stem cells from a partially matched donor, new research suggests. Children with SCID-X1 are born with a genetic defect that prevents them from developing a normal immune system. Because they are prone to life-threatening infections, infants with SCID-X1 must be kept in a sterile, protective bubble and require extensive treatment for survival beyond infancy.
Researchers have developed a new method to activate genes by synthetically creating a key component of the epigenome that controls how our genes are expressed. The new technology allows researchers to turn on specific gene promoters and enhancers -- pieces of our genomes that control our gene activity -- by chemically manipulating proteins that package our DNA.